MELINE ETHNIC SKIN NIGHT, is a highly active depigmentation emulsion developed specifically for night-time use to correct melasma and hyperpigmentation in dark and olive skin tones with phototypes IV–VI. It reduces melanin synthesis by suppressing tyrosinase enzyme expression at the mRNA level and lightens pigments by blocking melanosome release.
Retinal, a form of vitamin A much more potent than retinol, suppresses tyrosinase mRNA transcription and accelerates cell renewal. Ascorbic Acid (Vitamin C) reduces melanin synthesis and oxidation through tyrosinase inhibition and its strong antioxidant effect, while also supporting collagen synthesis. Arbutin provides powerful tyrosinase inhibition, suppressing melanocyte activity as a natural and safer alternative to hydroquinone.
Nonapeptide-1 (Melanostatine), as an antagonist of melanocortins, blocks the melanocyte-stimulating signal at its source. Cysteamine HCl inhibits tyrosinase and neutralizes melanin precursors; it is a modern active ingredient with comparable efficacy to hydroquinone but with a superior safety profile. Mandelic Acid provides safe, gentle exfoliation and inhibition of melanin transfer for dark skin types thanks to its large molecular structure, while Niacinamide supports skin tone equalization by preventing the transfer of melanosomes to keratinocytes and strengthens the barrier function.
The formulation for phototype IV–VI skin tones is customized with a selection of ingredients that minimize the risk of post-inflammatory hyperpigmentation. It is suitable for evening use only and forms an integrated day-night protocol with MeLine Ethnic Skin Day Cream.
Specifically formulated for individuals with dark and olive skin tones, defined as Fitzpatrick skin types IV–VI. It is suitable for those facing pigmentation issues such as melasma, pregnancy mask, sun spots, age spots, and post-inflammatory hyperpigmentation; those seeking to correct overall uneven skin tone; and those wishing to continue the home care protocol of the MeLine 01 Ethnic Skin clinical treatment. It can be used on normal, dry, oily, combination, and sensitive skin types; for beginners and those with sensitive skin, it is recommended to start with every-other-day use.
Evening
Cleanse face with MeLine Gentle Foam Cleanser.
Apply a thin layer over the entire face and gently massage until completely absorbed.
In case of irritation, apply every other day for the first two to three weeks before transitioning to daily use.
Use for a minimum of 90 days; total treatment duration is determined under the supervision of a specialist.
Retinal (Retinaldehyde): A much more powerful form of vitamin A than Retinol; it suppresses tyrosinase mRNA transcription, accelerates cell regeneration, and reduces melanosome transfer.
Ascorbic Acid (Vitamin C): Reduces melanin synthesis and oxidation through tyrosinase inhibition; provides strong antioxidant effects and supports collagen synthesis.
Arbutin: Suppresses melanocyte activity; provides tyrosinase inhibition as a natural and safe alternative to hydroquinone.
Mandelic Acid: Due to its large molecular structure, it provides gentle exfoliation safe for dark skin types and inhibits melanin transfer; it has a low risk of post-inflammatory hyperpigmentation.
Niacinamide (Vitamin B3): Prevents the transfer of melanosomes to keratinocytes, supports skin tone equalization, strengthens barrier function, and exhibits an anti-inflammatory effect.
Nonapeptide-1 (Melanostatine): As an antagonist of melanocortins, it blocks the melanocyte stimulating signal at its source and stops melanin production.
Cysteamine HCl: A powerful antioxidant and depigmenting agent; it inhibits tyrosinase and neutralizes melanin precursors. It is a modern active with comparable efficacy to hydroquinone and a superior safety profile.
Sodium Hyaluronate: Penetrates deep skin layers to provide intense hydration and maintain water balance.
Tocopheryl Acetate + Tocopherol (Vitamin E): Provides antioxidant protection; stabilizes the formula against oxidation, protecting Vitamin C and Retinal.
Dextran: A long-chain polysaccharide; forms a film in the formula, supporting the controlled release of active ingredients and providing a moisturizing effect.
Aqua, Cetyl Alcohol, Glycerin, Mandelic Acid, Ethylhexyl Methoxycinnamate, Ascorbic Acid, Arbutin, Niacinamide, Cetearyl Alcohol, Magnesium Sulfate, Tocopheryl Acetate, Glyceryl Stearate, Peg-100 Stearate, Titanium Dioxide, Sodium Hyaluronate, Nonapeptide-1, Dextran, Cysteamine Hcl, Phenoxyethanol, Benzyl Alcohol, Potassium Sorbate, Tocopherol, Sodium Metabisulfite, Retinal, Disodium Edta
This product is only suitable for nighttime use. Avoid daytime use and always apply sunscreen.
Because it contains Retinal, mild irritation, redness, or peeling may occur during initial use. Gradually incorporate the product into your routine.
Consult your doctor before use during pregnancy and breastfeeding. Avoid contact with the eye area.
Avoid simultaneous use with other acid-containing products. If you experience skin sensitivity, reduce or discontinue use.
